Association between polymorphisms in the human serotonin transporter gene and lifelong premature ejaculation in the Han population
نویسندگان
چکیده
منابع مشابه
Biallelic and Triallelic 5-Hydroxytyramine Transporter Gene-Linked Polymorphic Region (5-HTTLPR) Polymorphisms and Their Relationship with Lifelong Premature Ejaculation: A Case-Control Study in a Chinese Population
BACKGROUND This study aimed to explore the relationship between premature ejaculation (PE) and the serotonin transporter gene-linked polymorphic region (5-HTTLPR) with respect to the biallelic and triallelic classifications. MATERIAL AND METHODS A total of 115 outpatients who complained of ejaculating prematurely and who were diagnosed as having lifelong premature ejaculation (LPE) and 101 cont...
متن کاملPolymorphisms of the serotonin transporter gene and their relation to premature ejaculation in individuals from Iran.
PURPOSE This study tested whether individuals with at least 1 copy of the short (S) or long (L)(G) allele of the serotonin transporter gene-linked polymorphic region exhibit a greater incidence of premature ejaculation compared with L(A)L(A) individuals. MATERIALS AND METHODS The serotonin transporter gene-linked polymorphic region was genotyped in 82 men with lifelong premature ejaculation a...
متن کاملAssociation of STin2 Variable Number of Tandem Repeat (VNTR) Polymorphism of Serotonin Transporter Gene with Lifelong Premature Ejaculation: A Case-Control Study in Han Chinese Subjects
BACKGROUND The STin2 VNTR polymorphism has a variable number of tandem repeats in intron 2 of the serotonin transporter gene. We aimed to explore the relationship between STin2 VNTR polymorphism and lifelong premature ejaculation (LPE). MATERIAL AND METHODS We recruited a total of 115 outpatients who complained of ejaculating prematurely and who were diagnosed as LPE, and 101 controls without P...
متن کاملAssociation of STin2 VNTR Polymorphism in the SLC6A4 Gene with Increased Risk of MS Disease
Background: Multiple sclerosis (MS) is a chronic disease of the central nervous system (CNS) that is characterized by inflammation, demyelination and axonal injury. Although the etiology of MS disease is still unknown, many studies suggest that immune system dysfunction plays an important role in the pathogenesis of this disease. The serotonin serves as a mediator between CNS and the immune sys...
متن کاملEvaluation of VNTR polymorphisms of dopamine transporter gene and the risk of bipolar disorder in Zahedan, southeast Iran
The exact role of dopamine transporter gene (DAT1) in the pathogenesis of bipolar disorder type 1 (BD) is not understood. In the present study, we aimed to evaluate the possible association between 30, 40 and 63 bp variable number tandem repeat (VNTR) polymorphisms of DAT1 gene and the risk of type 1 (BD) in a sample of Iranian population. This case-control study was performed on 152 BD patient...
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عنوان ژورنال:
دوره 20 شماره
صفحات -
تاریخ انتشار 2018